The first acoustic research in Ukraine began in the middle of the 20th century with the creation of the Department of Acoustics and Sound Engineering at the Kyiv Polytechnic Institute and the Kyiv Research Institute of Hydrodevices. The first works were dedicated to the development of electroacoustic equipment, the study of acoustic features of the premises and the design of hydroacoustic buoys and stations. In the first years of the independent Ukraine, acoustic research was aimed at creating the projects of new state premises of complex shapes (sessional, conference halls, etc.). In 1991, the Department of Acoustics introduced the speciality ”Medical acoustic devices and equipment”. In recent years, the significant results have been achieved in the development of acoustic design and computing methods and in the construction of early passive ultrasound diagnostic devices as acoustothermometer used for measuring the internal temperature of the human body, and an auditory echoscope, which implemented a new method for diagnosing human hearing. In addition, after 2014 the department created and tested a technique for acoustic music therapy for the rehabilitation of individuals affected by the stressful situations. Much attention has been paid to the issues of acoustic signals processing and separating them from noise.