The investigation of listening comprehension in auditory and visually complex classroom settings is a promising method to evaluate children’s cognitive performance in a realistic setting. Many studies were able to show that children are more susceptible to noise than adults. However, it has recently been suggested that established monaural listening situations could overestimate the influence of noise on children’s task performance. Therefore, new, close-to real-life scenarios need to be introduced to investigate cognitive performance in everyday situations rather than artificial laboratory settings. This study aimed at extending a validated paper-and-pencil test towards a virtual reality setting and investigated different interaction methods using adult participants. In contrast to other recent studies, the virtual environment had little influence on this listening comprehension paradigm, since comparable results were obtained in the paper-and-pencil test and in the virtual reality variants for all user interfaces. Thus, the presented paradigm has proven to be robust and can be used to further investigate the usage of virtual reality to evaluate children’s cognitive performance.